New vaccine for cholesterol treatment

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A new vaccine, still in its early stages, has reduced low-density lipoprotein (LDL) cholesterol in both mice and monkeys with just one vaccination according to a recent study.

The vaccine targets a protein called PCSK9 that controls cholesterol levels in the blood. By manipulating PCSK9, the researchers are able to lower cholesterol in the blood,

LDL is “bad” cholesterol. High levels of LDL cholesterol can cause plaque in the arteries,  which increases the risk of heart attack, stroke and heart disease.

Researchers say the  vaccine may provide a more effective alternative to statins. Statins work by blocking an enzyme needed by the liver to produce cholesterol.

According to the Centers for Disease Control and Prevention (CDC),

  • 73.5 million adults (31.7 percent) in the United States have high LDL, or “bad,” cholesterol.
  • Fewer than 1 out of every 3 adults (29.5 percent) with high LDL levels has the condition under control.
  • Less than half (48.1 percent) of adults with high LDL levelsare getting treatment to lower their levels.
  • People with high total cholesterol have approximately twice the risk for heart disease as people with ideal levels.
  • Nearly 31 million adult Americans have a total cholesterol level greater than 240 mg/dL.

To learn how to control your LDL levels, click here.

 

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